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insitro and Bristol Myers Squibb Collaborate to Advance Drug Discovery for Amyotrophic Lateral Sclerosis (ALS)

Shots:

  • insitro & BMS have extended their 5yr. collaboration (2020) to discover novel small molecule therapies for ALS using insitro’s AI-enabled ChemML platform
  • The 1yr. extension will focus on developing therapies for a novel ALS target identified preclinically, with insitro receiving ~$20M in new funding & remaining eligible for discovery, development, regulatory, & commercial milestones exceeding $2B, plus royalties, under the 2020 deal
  • ChemML integrates advanced in silico & lab capabilities, incl. large-scale data generation (QALs), ML-based modeling (with Eli Lilly), an AI-driven design loop, & robust compute power with 192 H100 GPUs for rapid small-molecule optimization

Ref: Bristol Myers Squibb | Image: Bristol Myers Squibb and insitro| Press Release

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