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Orbis Medicines and Novo Partner on Oral Macrocycle Drugs in a ~$1.4B Deal

Shots:

  • Orbis Medicines has entered into a strategic collaboration & license agreement with Novo to discover & develop next-generation oral macrocycle therapeutics for cardiometabolic diseases 
  • As per the deal, Orbis will receive ~$1.4B in upfront, and development & commercial milestone payments, plus tiered royalties on future product sales, while Novo will also make a strategic investment in Orbis Medicines
  • Collaboration will leverage Orbis’ nGen platform, which combines generative AI & high-throughput synthesis. Its multi-parameter optimization engine designs nCycles with good drug-like properties & continuously improves them using a large, real-time experimental macrocycle dataset

Ref: Businesswire  |  Image: Orbis & Novo Press Release

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