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Merck Highlights P-III (KEYNOTE-B96/ENGOT-ov65) Trial Findings on Keytruda for Platinum-Resistant Ovarian Cancer

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  • Merck has reported P-III (KEYNOTE-B96/ENGOT-ov65) trial data assessing Keytruda (400mg, IV, Q6W for ~2yrs.) with CT ± Avastin vs PBO + CT ± Avastin in Pt-resistant recurrent ovarian cancer pts (n=643)
  • Trial met its 2EP of improved OS in pts with PD-L1+ tumors, building on previously reported data, which will be presented at ESMO’25; OS data to be reported in future
  • Additionally, data from P-II/III (REJOICE-Ovarian01) trial assessing raludotatug deruxtecan in pts with Pt-resistant high-grade ovarian primary peritoneal or fallopian tube cancer will also be presented at the ESMO’25

Ref: Merck  | Image: Merck | Press Release

Related News:- Merck Presents P-III (HYPERION) Trial Data of Winrevair (sotatercept-csrk) for Pulmonary Arterial Hypertension at ERS 2025

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