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ModeX Therapeutics (OPKO Health) Enters $1B+ Deal with Regeneron to Develop Multispecific Antibodies for Select Therapeutic Indications

Shots:

  • ModeX & Regeneron entered into a license & collaboration agreement to develop multispecific antibodies across cancer and metabolic, combining ModeX’s MSTAR platform with Regeneron’s antibody binders
  • Regeneron will fund & lead all development & commercialization in exchange for $7M upfront, plus future product selection, clinical, regulatory, & commercial milestones over $200M per molecule, with total deal value over $1B, if multiple products succeed, as well as tiered royalties up to low double digits at the highest tier
  • MSTAR platform creates multispecific antibodies using modular building blocks to enhance potency, precision, & simultaneous targeting of multiple disease pathways

Ref: ModeX Therapeutics | Image: ModeX Therapeutics and Regeneron | Press Release

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