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Gilead Sciences and Kymera Therapeutics Sign Exclusive Option and License Agreement to Develop Oral CDK2 Degraders

Shots:

  • Gilead signed a research partnership with Kymera to develop an oral molecular glue degrader (MGD) targeting cyclin-dependent kinase 2 (CDK2) for the treatment of breast cancer and other solid tumors
  • Kymera will receive a total of up to $85M in upfront and option exercise payments and is eligible for up to $665M, plus high single-digit to mid-teens tiered royalties on net product sales under the collaboration
  • Additionally, Kymera will be responsible for all research activities for the MGD CDK2. Gilead will have worldwide rights to develop, manufacture, and commercialize all MGD products resulting from the collaboration

Ref: Businesswire  | Image: Gilead & Kymera | Press Release

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