Shots:
Amgen announced that the CHMP issued a positive opinion recommending an expanded indication for Repatha (evolocumab) to reduce cardiovascular risk in adults with established or high risk for atherosclerotic cardiovascular disease by lowering LDL-C levels, alongside correction of other risk factors
The recommendation is supported by the P-III (VESALIUS-CV) study involving ≥12,000 pts., Repatha…
Shots:
Eli Lilly reported positive topline results from the P-III (ACHIEVE-4) study of Foundayo (orforglipron) vs insulin glargine in ~2,700 pts with type 2 diabetes, and obesity or overweight with elevated CV risk, meeting the 1EP of non-inferiority in MACE-4 events
Foundayo demonstrated a 16% lower risk of MACE-4 and 23% lower risk of MACE-3,…

