Shots:
AbbVie and Genmab announced positive topline results from the P-III (EPCORE DLBCL-2) study, demonstrating a statistically significant and clinically meaningful improvement in PFS vs R-CHOP alone (SoC) in newly diagnosed diffuse large B-cell lymphoma (DLBCL) pts. with an IPI score of 2-5
The study evaluated fixed treatment duration epcoritamab(SC) plus rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and…
Shots:
Abbott received US FDA approval for updates to the CardioMEMS HF System, enabling patients in the US to view their pulmonary artery pressure (PAP) readings through the CardioGuide HF App
The updated system includes Dynamic Treatment Plan (DTP), allowing care teams to create personalized medication adjustment plans based on changes in PAP and send…
Shots:
Merck & Co., Bristol-Myers Squibb, and Johnson & Johnson led the oncology market in 2025, generating $35.86B, $26.58B, and $25.38B, respectively. Growth was supported by strong demand for established therapies, newer product launches, and broader use across indications
The global oncology market is projected to grow from $279.73B in 2026 to $732.45B by 2035,…
Shots:
Mounjaro/Zepbound, Keytruda, and Dupixent emerged among the leading prescription drug products in 2025, generating $36.51B, $31.68B, and $18.48B, respectively. Strong patient demand, expansion across approved indications, broader access, market-share gains, and new clinical and regulatory milestones continued to shape the performance of the leading prescription therapies
The global prescription drugs market was valued at…
Shots:
AstraZeneca reported full results from the P-III OBERON and TITANIA studies, showing that tozorakimab 300 mg Q4W reduced moderate-to-severe COPD exacerbations versus PBO in pts. receiving inhaled standard of care
In the primary population of former smokers, tozorakimab reduced exacerbations by 29% in OBERON and 34% in TITANIA, while reductions in the overall population…
Shots:
Definium Therapeutics announced that the US FDA granted BTD to DT120 (lysergide) orally disintegrating tablet (ODT) for the treatment of major depressive disorder (MDD), following positive P-III results
In the P-III Emerge study, a single 100 µg dose of DT120 ODT demonstrated an 8.1-point PBO-adjusted improvement in MADRS total score at wk. 6 (p<0.0001),…
Shots:
Belite Bio submitted a New Drug Application (NDA) to Japan’s MHLW for once-daily oral tinlarebant (LBS-008) for the treatment of Stargardt disease type 1 (STGD1)
The NDA was submitted under Japan’s Sakigake Designation System, following tinlarebant’s designation as a Sakigake pharmaceutical product; if approved, it could become the first approved treatment for STGD1 and…
Shots:
Novartis announced that the P-III HARBOR study of delpacibart etedesiran (del-desiran) in people with myotonic dystrophy type 1 (DM1) did not meet its 1EP of video hand opening time (vHOT)
Del-desiran showed evidence of clinical activity in 2EPs and exploratory analyses, while safety findings were generally consistent with previously reported data; Novartis is evaluating…
Shots:
Upstream Bio presented results from the P-II VALIANT study evaluating verekitug in 478 adults with severe asthma, with the study meeting its 1EP of reducing the annualized asthma exacerbation rate (AAER) across all dose regimens.
Verekitug 100 mg dosed every 12 wks. reduced AAER by 56% vs. PBO (p<0.001) and also improved lung function…
Shots:
Nyxoah announced the first patient implantation in BREATHE, its US post-approval study evaluating the long-term safety and effectiveness of the Genio System in adults with moderate to severe obstructive sleep apnea (OSA)
The prospective, multicenter study plans to implant up to 229 pts. across up to 25 US centres, with follow-up for up to…

