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Tempest Therapeutics Enters Exclusive Option Agreement with Senlang for In Vivo CAR-T Platform and Pipeline

Shots:

  • Senlang has granted Tempest an exclusive option to license its CD7-targeted lentiviral vector platform & in vivo CAR-T portfolio, incl. a BCMA/GPRC5D dual-targeting candidate for R/R MM & additional assets for hematologic malignancies & autoimmune diseases
  • Senlang’s platform uses targeted lentiviral vectors to deliver CAR transgenes to endogenous CD7+ T cells and NK cells, generating CAR-T & CAR-NK cells directly in pts without individualized cell collection or external manufacturing required
  • The BCMA/GPRC5D dual-targeting candidate is being evaluated in an ongoing P-I dose-escalation study in R/R MM, while Tempest & Senlang will continue to assess the P-I results & broader portfolio during the option period

Ref: Globenewswire  |  Image: Senlang & Tempest |  Press Release

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