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UCB Presents Efficacy and Safety Results of Zilucoplan and Rozanolixizumab in P-III (RAISE) & (MycarinG) Study for Generalized Myasthenia Gravis at MGFA 2022

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UCB Presents Efficacy and Safety Results of Zilucoplan and Rozanolixizumab in P-III (RAISE) & (MycarinG) Study for Generalized Myasthenia Gravis at MGFA 2022

UCB Presents Efficacy and Safety Results of Zilucoplan and Rozanolixizumab in P-III (RAISE) & (MycarinG) Study for Generalized Myasthenia Gravis at MGFA 2022

Shots:

  • The P-III (RAISE) study evaluates zilucoplan (0.3mg/kg, SC) in a ratio (1:1) in 174 patients & the P-III (MycarinG) study evaluates rozanolixizumab (7/10mg/kg) in 200 adults with gMG. The regulatory submissions are expected in 2022
  • The (RAISE) study met its 1EPs & 2EPs i.e., mean improvement in MG-ADL score @12wk. along with other scores @1wk., safety profile & tolerability were consistent with prior data, TEAEs (76.7% vs 70.5%)
  • In (MycarinG) study, reduction in MG-ADL from baseline to Day 43 at ~7/10mg/kg doses while ≥70% in IgG levels (71 %/78%), anti-AChR autoantibody levels decreased with total IgG reduction, TEAEs (81.3%/82.6% vs 67.2% for PBO), baseline characteristics were well balanced

Ref: UCB | Image: UCB

Click here to­ read the full press release 

Neha

Neha Madan is a content writer at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots.

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