Shots:
- Rigel has reported the availability of Veppanu (vepdegestrant) by prescription in the US for the treatment of adults with ER+/ HER2-, ESR1-mutated advanced or metastatic breast cancer, with disease progression following ≥1L of endocrine therapy
- Veppanu (200mg, PO, QD) is an FDA-approved PROTAC, a class of targeted protein degraders that uses the body’s natural machinery to selectively eliminate disease-causing proteins rather than simply inhibit them
- In May 2026, Rigel entered into an exclusive, global license agreement with Arvinas & Pfizer to develop, manufacture & commercialize Veppanu
Ref: PRnewswire | Image: Rigel | Press Release
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