Agenus Completes Strategic Collaboration with Zydus Lifesciences of ~$141M to Advance BOT+BAL Development & Expand US Manufacturing
Shots:
- Agenus has completed its strategic collaboration with Zydus Lifesciences to accelerate global development and potential commercialization of the BOT+BAL immunotherapy program
- As per the deal, Zydus gave $75M upfront payment to Agenus for US biologics manufacturing facilities, and Agenus is also eligible for Contingent Milestone Payments ~$50M in production-linked milestones. Zydus acquired common stock of Agenus $16M (~2.1M shares), and also receives an exclusive BOT+BAL license for India and Sri Lanka, with Agenus earning a 5% royalty on net sales
- In 2025, BOT+BAL showed a 42% two-year OS and a mOS of 21 mos in 3L or later MSS mCRC patients without active liver metastases, prompting Agenus and CCTG to launch the global P-III trial (BATTMAN), now open for enrollment
Ref: Agenus | Image: Agenus and Zydus Lifesciences | Press Release
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