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Camurus Reports Topline P-IIb (POSITANO) Trial Data on CAM2029 for Symptomatic Polycystic Liver Disease

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  • Camurus has reported topline P-IIb (POSITANO) trial data assessing 2 dosing regimens of CAM2029 (octreotide SC depot) vs PBO in 71 pts with symptomatic polycystic liver disease (PLD), with pts continuing treatment in a 2.5yr. OLE study
  • Trial met its 1EP with a 4.3% relative reduction in height-adjusted liver volume at Wk. 53 for combined CAM2029 groups & an 8.7% reduction in total liver cyst volume; improvements across disease symptoms as well as pts & clinical reported outcomes were also observed. Data to be presented in future meeting
  • CAM2029 is also being assessed in an ongoing P-III (SORENTO) trial for GEP-NET, plus a follow-up P-III study for symptomatic PLD is planned for discussion with regulatory authorities

Ref: Prnewswire | Image: Camurus| Press Release

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