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Johnson & Johnson Reports P-IIIb (APEX) Trial Findings of Tremfya for Active Psoriatic Arthritis

Shots:

  • J&J has reported P-IIIb (APEX) trial data assessing Tremfya vs PBO in biologic-naïve PsA pts with inadequate response to standard therapies for 24wks., followed by a 12wk. safety follow-up; eligible pts could enter a 2yr. extension phase prior to the final safety follow-up
  • Trial met its 1EP of improved ACR20 response, showing reduced signs & symptoms as well as its 2EP of less structural damage progression per PsA-modified vdH-S score, incl. joint space narrowing & erosion at 24wks.; data to be highlighted in future conferences   
  • APEX trial will continue to evaluate the sustained efficacy of Tremfya in inhibiting structural damage in pts with active PsA

Ref: J&J | Image: J&J

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