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ABL Bio Licenses Grabody-B Brain Delivery Platform to GSK for ~$2.76B (£2.15B)

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ABL Bio & GSK

ABL Bio Licenses Grabody-B Brain Delivery Platform to GSK for ~$2.76B (£2.15B)

Shots:

  • ABL Bio has entered into a global licensing agreement with GSK for its Grabody-B BBB shuttle platform to develop therapies targeting various novel pathways using antibodies, siRNA, & ASOs for neurodegenerative diseases
  • As per the deal, GSK will handle preclinical & clinical activities, manufacturing, & marketing of the potential programs in exchange for ~$99.4M, incl. $49.6M upfront, research milestones & potential expansion fee, with ~$2.67B in R&D, regulatory & marketing milestones, plus net sales-based tiered royalties, while ABL Bio will handle tech transfer   
  • Grabody-B targets IGF1R to overcome the BBB, improving drug penetration & allowing efficient drug delivery in the brain

Ref: Prnewswire | Image: ABL Bio & GSK

Related News:- ABL Bio Collaborates with Merck to Develop ABL103 Plus Keytruda for Treating Solid Tumors

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Ridhi Rastogi

Ridhi is an avid secondary researcher who follows trends in the biopharmaceutical and healthcare sectors to curate engaging content for the global audience. She works as a news editor at PharmaShots and loves to read books and explore new destinations.

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