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Eli Lilly Enters a ~$1.4B Licensing Agreement with Sangamo Therapeutics for its STAC-BBB Capsid

Shots:

  • Sangamo has granted Eli Lilly global exclusive license of STAC-BBB for one initial CNS target, with an option to add up to 4 more targets upon payment of additional license fees, allowing IV delivery of Lilly’s genomic medicines for CNS diseases
  • As per the deal, Lilly will handle R&D, regulatory activities, manufacturing, & global marketing of products from the alliance in exchange for $18M upfront license fee & ~$1.4B in additional target fees & milestones across 5 potential neurology targets, plus net sales-based tiered royalties, while Sangamo will handle STAC-BBB tech transfer
  • STAC-BBB is a neurotropic AAV capsid that has depicted strong BBB penetration & effective neuronal transduction in nonhuman primates

Ref: Businesswire | Image: Eli Lilly & Sangamo 

Related News:- Eli Lilly Reports P-II (ALPACA) Trial Data of Lepodisiran for Heart Diseases

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