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Merck Partners with Jiangsu Hengrui Pharmaceuticals for HRS-5346, Expanding its Cardio-Metabolic Portfolio

Shots:

  • Merck has entered into an exclusive license agreement with Jiangsu Hengrui Pharmaceuticals for HRS-5346
  • As per the deal, Merck has obtained exclusive rights to develop, manufacture & commercialize HRS-5346 globally excl. Greater China region in exchange for $200M upfront & ~$1.77B in development, regulatory & commercial milestones, along with net sales-based royalties; closing expected in Q2’25
  • HRS-5346 is an oral, small molecule lipoprotein(a) inhibitor that is being investigated in a P-II trial in China for cardio-metabolic diseases

Ref: Merck | Image: Merck & Jiangsu Hengrui

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