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Alumis and Kaken Pharmaceutical Enter Collaboration & Licencing Deal for ESK-001’s Development & Commercialization in Japan

Shots:

  • Alumis & Kaken have partnered to develop, manufacture, & market ESK-001 for dermatology in Japan, with an option to expand into rheumatology & GI diseases
  • As per the deal, Kaken will handle development, approval & marketing of ESK-001 in Japan in exchange for $40M upfront & near-term co-development costs, with ~$140M in milestones & field option payments, plus net sales-based tiered royalties. Global development will be partially co-funded, with Alumis retaining rights in other regions
  • ESK-001 is being investigated in P-IIb trial for SLE & P-III (ONWARD) program for 24wks., incl. 2 P-III (ONWARD1 & 2) trials for mod. to sev. Plaque PsO, after which pts could opt for an LTE study

Ref: Globenewswire | Image: Alumis & Kaken

Related News:- Alumis Signs a Definitive Merger Agreement with ACELYRIN to Develop Novel Therapies for Immune-mediated Diseases

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