AstraZeneca Reports CHMP Positive Opinion for Imfinzi to Treat Limited-Stage Small Cell Lung Cancer (LS-SCLC)
Shots:
- The CHMP has recommended Imfinzi for the treatment of LS-SCLC pts whose disease has not progressed after receiving Pt-based CRT; regulatory review underway in Japan & other regions
- Opinion was based on P-III (ADRIATIC) trial (n=730) assessing Imfinzi (1500mg, IV, Q4W) with or without Imjudo (75mg, IV, Q4W × 4 cycles) followed by Imfinzi (for ~24mos.) vs. PBO
- Study showed reduced risk of death by 27% (mOS: 55.9 vs 33.4mos.), where 57% vs 48% pts were alive at 3yrs. & it also depicted improved PFS by 24% (mPFS: 16.6 vs 9.2mos.), where 46% vs 34% pts had no disease progression at 2yrs. Data was published in The NEJM
Ref: AstraZeneca | Image: AstraZeneca
Related News:- AstraZeneca and Daiichi Sankyo Receive CHMP’s Positive Opinion for Datroway to Treat HR+/HER2- Breast Cancer
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Ridhi is an avid secondary researcher who follows trends in the biopharmaceutical and healthcare sectors to curate engaging content for the global audience. She works as a news editor at PharmaShots and loves to read books and explore new destinations.
