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Oak Hill Bio Enters an Exclusive Licensing Agreement with Roche for Rugonersen

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  • Oak Hill Bio has entered into an exclusive license agreement with Roche to obtain global rights of rugonersen (RO7248824) for the treatment of angelman syndrome
  • Oak Hill to initiate a pivotal P-III trial of rugonersen for angelman syndrome in early 2026, pending regulatory review of the final trial protocol
  • TANGELO study led by Roche, assessed rugonersen (ASO) vs natural history, which showed positive exploratory effects on multiple clinical measures & EEG delta power; data was presented at FAST’s Global Science Summit 2024

Ref: Oak Hill Bio | Image: Oak Hill Bio & Roche

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