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20 Contract Development and Manufacturing Organizations (CDMO) of 2024

Shots:

  • CDMOs are at the forefront of pharmaceutical manufacturing, shaping the industry’s growth by meeting the increasing global demand for pharmaceutical products
  • In 2023, the global CDMO market was valued at $224.86B, with projections to reach $465.14B by 2032, demonstrating a CAGR of 8.5%
  • PharmaShots presents a comprehensive report on the 20 Contract Development and Manufacturing Organizations of 2024
CompaniesFounded YearTotal Employees
Eurofins198762000
WuXi AppTec200038134
Charles River Laboratories194721800
Lonza189718000
Catalent200716900
Sun Pharma198315999
WuXi Biologics201012740
West Pharmaceutical Services192310600
MilliporeSigma (Merck)195410000
Patheon (ThermoFisher)197410000
Syngene19938146
Akum20047388
Piramal Pharma Solutions19846295
Samsung Biologics20114286
Siegfried18733700
AGC Biologics20182500
Bachem19712009
Emergent Bioservices19981600
Aurigene (Dr. Reddy)20021000
Lifecore Biomedical, Inc.1965524

Note: Columns 1 and 2 represent the Companies and Founded Year, while Columns 3 showcase the total employee’s in 2023

20. Lifecore Biomedical

Founded Year: 1965

Total Employees: ~500

Headquarters: Minnesota

  • Incepted in 1965, Lifecore Biomedical is a parenteral CDMO specializing in the development of small molecules, monoclonal antibody (mAb) fragments, hydrogels, microparticles, proteins, modified sodium hyaluronate, polymers, emulsions, and synthetic peptides
  • Lifecore Biomedical provides specialty services in formulation, aseptic filling, and final packaging for injectable medical devices and pharmaceutical drug products. Within its CDMO division, Lifecore has manufactured over 20 approved injectable products containing sodium hyaluronate
  • In Oct’23, SHL Medical entered into a co-marketing agreement with Lifecore Biomedical to enhance CDMO offerings and provide optimized solutions for drug delivery device development

19. Aurigene (Parent: Dr. Reddy’s)

Founded Year: 2002

Total Employees: 1000

Headquarters: Bangalore, Karnataka

  • Aurigene, a subsidiary of Dr. Reddy’s, operates as a CRDMO (Contract Research, Development, and Manufacturing Organization). The company has R&D centers in Bangalore and Hyderabad, along with manufacturing facilities in the UK, Mexico, and India
  • With over 25 years of experience in drug discovery, Aurigene offers comprehensive services, ranging from target identification to IND filing and commercialization of both small and large molecules for innovator companies worldwide
  • In May’23, Aurigene Pharmaceutical Services expanded its biologics CDMO (Contract Development and Manufacturing Organization) capacity by establishing a new biomanufacturing facility at Genome Valley

18. Emergent BioServices (Parent: Emergent BioSolutions)

Founded Year: 1998

Total Employees: ~1600

Headquarters: Maryland, United States

17. Bachem

Founded Year: 1971

Total Employees: ~2000

Headquarters: 2009

  • Bachem is an innovative company specializing in the development and manufacturing of peptides and oligonucleotides. Headquartered in Switzerland, the company operates globally with a presence in Asia, Europe, and the United States
  • With over 50 years of expertise, Bachem supports biopharma companies worldwide across research, clinical development, and product commercialization. Its comprehensive services include CMC (Chemistry, Manufacturing, and Controls) production, API (Active Pharmaceutical Ingredient) commercialization, and research support
  • In Mar’23, Bachem signed a long-term cooperation agreement valued at over $594.28M to develop and manufacture peptides, with production expected to commence between 2027 and 2031

16. AGC Biologics

Founded Year: 2018

Total Employees: 2500

Headquarters: Washington, United States

  • In 2016, all shares of CMC Biologics were acquired by AGC Asahi Glass (AGC), a Japan-based manufacturer specializing in glass, chemicals, and high-tech materials. Following this acquisition, AGC Biologics was established in January 2018 as a CDMO (Contract Development and Manufacturing Organization). This new entity resulted from the integration of Asahi Glass Company (AGC) Bioscience, Biomeva GmbH (Heidelberg, Germany), and CMC Biologics
  • AGC Biologics focuses on the development and manufacturing of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), mRNA, viral vectors, and genetically engineered cells
  • In Oct’23, AGC Biologics and Medigene entered into a TCR-T cell services agreement to support the development of Medigene’s new cell therapy product

15. Siegfried  

Founded Year: 1873

Total Employees: 3700

Headquarters: Zofingen, Switzerland

  • Siegfried is a leading CDMO with a global network of 13 production sites across seven countries on three continents. The company offers contract development and manufacturing services for APIs, intermediates, and finished dosage forms
  • Siegfried provides a range of services, from process development and optimization to registration, production, packaging, and logistics, all under one roof. The company specializes in complex oral, sterile, ophthalmic, and inhalation formulations, as well as viral vectors and associated technologies for custom development, manufacturing, and licensing
  • In Jan 2023, Intra-Cellular Therapies entered into an agreement with Siegfried for the manufacture and supply of the API for their product Caplyta

14. Samsung Biologics                      

Founded Year: 2011

Total Employees: 4300

Headquarters: Songdo, Incheon, Republic of Korea

  • Samsung Biologics, the biotech arm of Samsung Group, operates four manufacturing plants, with a fifth set to become operational in 2025. The company has established partnerships with major pharmaceutical companies, including Pfizer, GlaxoSmithKline, Eli Lilly, and AstraZeneca, to support a range of products
  • Samsung Biologics provides a comprehensive suite of services, including cell line development, final aseptic fill/finish, and laboratory testing, to support each stage of biopharmaceutical product development and manufacturing
  • In Jun’23, Samsung Biologics expanded its collaboration with Pfizer for the long-term manufacturing of its biosimilars portfolio

13. Piramal Pharma Solutions

Founded Year: 1984

Total Employees: 6300

Headquarters: Mumbai, India

  • Piramal Pharma Solutions, a global leader in developing and manufacturing APIs, also specializes in biologics. The company operates in over 30 countries and has a strong presence in more than 100 markets worldwide
  • The company offers a range of services, from drug discovery and development to manufacturing and antibody-drug conjugation, establishing itself as a well-known CDMO. Its primary markets include North America, Europe, and Asia
  • In May’23, Plus Therapeutics and Piramal Pharma Solutions expanded their collaboration to produce additional cGMP-compliant liposome drug products in response to the growing demand for Plus Therapeutics’ lead radiotherapeutic, Rhenium Obisbemeda

12. Akums Drugs and Pharmaceuticals

Founded Year: 2004

Total Employees: 7300

Headquarters: Delhi, India

  • Akums is a pharmaceutical contract manufacturer specializing in APIs, pharmaceuticals, cosmetics, dermatology products, and nutraceuticals. The company is internationally recognized and holds a WHO-GMP certification
  • With a network of over 100 partners, Akums offers comprehensive services spanning from innovation to commercialization. These services include regulatory expertise in drug approvals and patents in India
  • In Feb’23, Akums collaborated with Lyrus Life Sciences on patented technologies and formulations

11. Syngene

Founded Year: 1993

Total Employees: ~8100

Headquarters: Bangalore, India

  • Syngene, a subsidiary of Biocon, is a contract research, development, and manufacturing organization with expertise spanning the pharmaceutical, biotechnology, animal healthcare, consumer goods, and agrochemical industries
  • Syngene provides development and manufacturing capabilities for a range of drug modalities, including small molecules, biologics, peptides, oligonucleotides, mRNA therapies, and CAR-T treatments, across pre-clinical, clinical, and commercial applications
  • In Dec’23, Syngene acquired Stelis Biopharma’s biologics manufacturing facility, increasing its biologics manufacturing capacity by 20,000 liters

10. Patheon (Parent: Thermo Fisher)

Founded Year: 1974

Total Employees: 10000

Headquarters: Massachusetts, United States

  • In 2017, Thermo Fisher Scientific acquired the CDMO Patheon for approx.      $7.2 billion. Through this acquisition, Thermo Fisher provides comprehensive pharmaceutical services for drug development, clinical trial logistics, and commercial manufacturing
  • The company operates in 60+ locations worldwide, with manufacturing sites across the United States, Europe, Australia, and key regions in Asia. Patheon offers services across all stages of development, including APIs, biologics, viral vectors, cGMP plasmids, formulations, clinical trial solutions, logistics, as well as commercial manufacturing and packaging
  • In Mar’23, Thermo Fisher Scientific announced a partnership with UCSF to accelerate cell therapy development and expand manufacturing capabilities through a new facility in San Francisco

9. MilliporeSigma (Merck)

Founded Year: 1954

Total Employees: 10000

Headquarters: Massachusetts, United States

  • MilliporeSigma, a division of Merck KGaA, operates as a CDMO, providing a range of services to the life sciences and pharmaceutical sectors. The division was formed following Merck’s acquisition of Millipore in 2010 and Sigma-Aldrich in 2015
  • MilliporeSigma’s service offerings span across preparation, separation, filtration, and monitoring processes. The company focuses on three core business areas: Research Solutions, Process Solutions, and Applied Solutions, delivering products and services tailored to these specific fields
  • In Sep’23, Merck’s MilliporeSigma announced the launch of fully integrated mRNA services, covering development, manufacturing, and commercialization stages

8. West Pharmaceutical Services

Founded Year: 1923

Total Employees: ~10600

Headquarters: Pennsylvania, USA

  • Founded in 1923, West Pharmaceutical Services is a global CDMO specializing in high-quality, innovative containment and delivery solutions for pharmaceutical companies
  • With over 40 manufacturing facilities across three continents, West Pharmaceutical Services provides a range of services, including drug handling solutions, regulatory support, contract manufacturing, packaging solutions, analytical services, and fill-finish support
  • In Feb’23, West Pharmaceutical Services and Corning expanded their collaboration by launching their first product, the West Ready Pack featuring Corning Valor RTU Vials

7. WuXi Biologics

Founded Year: 2010

Total Employees: ~12700

Headquarters: Jiangsu, China

  • WuXi Biologics is a leading CDMO with expertise in biologics development and manufacturing. The company operates 20 research and manufacturing facilities across China, Ireland, Germany, the United States, and Singapore
  • With more than six open-access platforms for development and production, WuXi Biologics provides end-to-end services to over 600 partners worldwide
  • In Aug’23, WuXi XDC and Boostimmune signed a memorandum of understanding (MOU) for integrated services, granting Boostimmune access to WuXi XDC’s bioconjugate platform and expertise

6. Sun Pharma

Founded Year: 1983

Total Employees: ~16000

Headquarters:  Mumbai, India

5. Catalent

Founded Year:  2007

Total Employees: ~16900

Headquarters: New Jersey, United States

  • Catalent is a multinational corporation headquartered in the United States. The company operates under two primary business segments: Biologics and Pharma & Consumer Health. Initially established in 2007, Catalent went public in 2014
  • The Development and Clinical Services segment provides a range of services, including manufacturing, packaging, storage, and inventory management for clinical trials. Its Oral Technologies segment offers formulation, development, and manufacturing services for oral dose forms. Sterile Technologies encompasses both proprietary and conventional dosage forms for various administration routes. Packaging Services cover packaging solutions for pharmaceuticals, biologics, consumer health, and veterinary products
  • In Aug’23, MindMed Entered into an Exclusive License Agreement with Catalent for Patented Zydis Fast-Dissolve Technology Incorporated in MM-120

4. Lonza

Founded Year: 1897

Total Employees: 18000

Headquarters: Basel, Switzerland

  • Based in Switzerland, Lonza combines technological innovation with advanced pharmaceutical manufacturing
  • The company partners with biopharma and nutrition organizations to deliver a broad spectrum of services, from early-phase research and custom development to the production of APIs and innovative dosage forms for the pharma, consumer health, and nutrition sectors
  • In Oct’23, Lonza expanded its collaboration with Vaxcyte to support the commercial manufacturing of broad-spectrum pneumococcal conjugate vaccines for global distribution

3. Charles River Laboratories

Founded Year: 1947

Total Employees: ~22,000

Headquarters: Massachusetts, United States

  • Charles River Laboratories provides a wide range of preclinical and clinical laboratory services, including gene and cell therapy support, to pharmaceutical, medical device, biotechnology industries, and government agencies
  • The company offers integrated solutions to healthcare innovators, with services in cell sourcing, research models, biologics testing, CDMO services, QC microbial solutions, and regulatory expertise
  • In Oct’23, Aitia partnered with Charles River to advance therapies for neurodegenerative diseases and oncology, leveraging Charles River’s drug development platform

2. WuXi AppTec

Founded Year: 2000

Total Employees: ~38,100

Headquarters: Shanghai, China

  • WuXi AppTec offers a broad portfolio of R&D, drug testing, and manufacturing services across Asia, Europe, and North America. Its end-to-end services include chemistry-focused CRDMO capabilities and cell and gene therapy CTDMO (Contract Testing, Development, and Manufacturing Organization) solutions
  • The company’s CRDMO platform supports the development and manufacturing of small molecules, oligonucleotides, and peptides. As a CTDMO, WuXi AppTec provides comprehensive services for advanced biopharmaceuticals, including gene and cell therapies
  • In Jan’23, Pasithea Therapeutics entered into an agreement with WuXi STA, a WuXi AppTec subsidiary, to manufacture and supply API for its candidate, PAS-004

1. Eurofins

Founded Year: 1987

Total Employees: 62,000

Headquarters: Van Fleuri, Luxembourg

  • Eurofins Scientific specializes in testing across various industries, including food, environment, pharmaceuticals, and cosmetics, as well as in discovery pharmacology, forensics, advanced material sciences, agriscience, contract research services, genomics, clinical study support, and biopharma contract development and manufacturing
  • Eurofins offers a range of, integrated end-to-end solution for preclinical and clinical outsourcing services, supporting the development of APIs and drug products for both biologics and small molecules
  • In Jan’23, Eurofins announced the establishment of a fully equipped laboratory campus in Genome Valley, Hyderabad, India

Sources:

  • Annual reports
  • SEC Filings
  • Press releases
  • Company 

Related Post: 20 Contract Development and Manufacturing Organizations (CDMOs) of 2022

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