Tags : Tuberculosis

Pharma

Gates Foundation Forms an Alliance with Global Pharma Companies to

Shots: GSK, Evotec, J&J, Otsuka, the Bill & Melinda Gates Medical Research Institute and its foundation have launched the ‘PAN-TB collaboration’ project to collaboratively accelerate the development of novel TB treatment regimens The global collaboration will focus on developing a new regimen with the drug candidates that demonstrated efficacy in its P-II studies with limited […]Read More

Biotech

BioNTech Signs an Agreement with Gates Foundation to Develop Therapies

Shots: Gates Foundation to fund $55M which may extend up to $100M for the development of preclinical vaccine and immunotherapy candidates preventing HIV and tuberculosis infection. BioNTech will retain rights to commercialize candidates in developed countries while providing affordable access to the candidates in developing countries The agreements will further expand the BioNTech’s infectious disease […]Read More

Regulatory

TB Alliance’s Pretomanid Combination Therapy Receives the US FDA’s Approval

Shots: The approval is based on the Nix-TB trial assessing bedaquiline, pretomanid and linezolid collectively called BPaL regimen in 109 patients with XDR-TB treatment-intolerant or non-responsive MDR-TB across three sites in South Africa The study demonstrated successful outcomes in @6mos. 95/107 patients and for two of the patients the study was extended to nine months. […]Read More