Active Ingredient: Aflibercept
Strength: 2 mg (0.05 mL)
Dosage Form: Injection (intravitreal)
Mechanism of Action: VEGF-A and PlGF inhibitors
First Approval: US (18 Nov 2011), EU (27 Nov 2012)
Revenue1
EYLEA net sales represent a significant portion of the total revenues for both Regeneron and Bayer. Both companies jointly commercialize the product Regeneron records net product sales of EYLEA in…
Active Ingredients: Ustekinumab
Strength: 45 mg/0.5 mL or 90 mg/mL (SC), 130 mg/26 mL (IV)
Dosage Form: Injection
Mechanism of Action: Interleukin 12 & 23 inhibitor
First Approval: US (25 Sep, 2009), EU (16 Jan, 2009)
Revenue1
Stelara is the leading blockbuster drug of Johnson & Johnson. Stelara contributed 9.7% of the Company's total revenues for 2021. Stelara up took…
Active Ingredients: Apixaban
Strength: 2.5 mg and 5 mg
Dosage Form: Tablet
Mechanism of Action: Factor Xa inhibitors
First Approval: US (Dec 28, 2012), EU (May 18, 2011)
Revenue1
Eliquis is a leading novel oral anticoagulant of BMS. The revenue for BMS continued to grow due to Eliquis and other recently launched new products. BMS and Pfizer jointly develop and…

