Shots:
Innovent has reported the P-III (RESTORE-3) trial data assessing Sycume(teprotumumab N01/IBI311) vs PBO in Chinese pts (n=116) with inactive thyroid eye disease (bilateral CAS ≤ 2 points)
Trial met its 1EP at Wk. 24, showing higher proptosis response rate as compared to PBO (60.4% vs. 23.5%), plus in 2EP, Sycume showed LS Mean change…
Shots:
China’s NMPA has approved Sycume for the treatment of thyroid eye disease (TED)
Approval was based on P-III (RESTORE-1) trial in TED pts, which met its 1EP in 2024, with 85.8% pts achieving ≥2mm proptosis reduction at 24wks., along with improved inflammation & QoL; data was presented at WOC, CSE, and CCOS
Sycume (teprotumumab…

