Tags : r/r

Celltrion Report Results of Truxima (biosimilar, rituximab) Based Regimen in

Shots: Celltrion has presented the result of P-II study that showed that regimen of Truxima (375mg/m2) + lenalidomide (20mg, day 1-21, qd) + acalabrutinib (100mg, day 1-28, bid) (R2A) is well-tolerated and effective in relapsed/refractory aggressive B-cell lymphoma In the 13 patients who underwent disease assessment following the R2A regimen, ORR (69%) and CR (31%), […]Read More

Triumvira’s TAC01-CD19 Receives FDA’s Fast Track Designation for R/R Diffuse

Shots: The US FDA has granted FT designation to Triumvira’s TAC01-CD19 for patients with relapsed or refractory Diffuse Large B-Cell Lymphoma (DLBCL) prior treated with at least two systemic therapies The TAC technology will significantly improve the limitation of existing cell therapies, including the risk of cytokine release syndrome and neurotoxicity, expanding treatment option for […]Read More

BMS’s Triple Regimen Receives European Commission Approval for Relapse/Refractory Multiple

Shots: The approval is based on P-II ELOQUENT-3 study assessing Empliciti (elotuzumab) + pomalidomide and low-dose dexamethasone (EPd) vs pomalidomide and low-dose dexamethasone (Pd) in 117 patients with r/r MM prior treated with 2L+ therapies including lenalidomide and a proteasome inhibitor (PI) with disease progression on the last therapy The P-III ELOQUENT-3 study results: The […]Read More

BMS’ Triple Regimen Receives Positive CHMP Recommendation for its Approval

Shots: The opinion is based on P-II ELOQUENT-3 study assessing Empliciti (elotuzumab) + pomalidomide and dexamethasone (EPd) vs pomalidomide + dexamethasone (Pd) in 117 patients in a ratio (1:1) with multiple myeloma prior treated with 2L+ therapies including lenalidomide and a proteasome inhibitor The CHMP recommendation will be reviewed by the European Commission to approve […]Read More

BeiGene Reports Updated Results of Tislelizumab in P-II Study in

Shots: The P-II (NCT03209973) study result involves assessing of tislelizumab (200mg, IV, q3w) as a monothx. in 70 patients with R/R to autologous stem cell transplantation (ASCT) or 2L+ r/r cHL The P-II study results: high anti-tumor activity in patients; ORR (87.1%); CR (62.9%); PR (24.3%); @12mos. PFS (73.8%); well tolerated; presented at 24thCongress of […]Read More