Shots:
The US FDA has approved Brinsupri (10 & 25mg) for treating NCFB pts (≥12yrs.); it is now available in the US. MAA is under EMA & MHRA review with a Japan filing planned in 2025 & potential launches in 2026 pending approvals
Approval was based on P-III (ASPEN) trial (n=1721) & P-II (WILLOW) trial…
Shots:
Fosun Pharma has granted Expedition global rights to develop, manufacture, & commercialize XH-S004, excl. Mainland China, Hong Kong SAR, & Macau SAR, where Fosun will retain its rights
As per the deal, Fosun will receive $120M incl. upfront & development milestone payments, with ~$525M in sales milestones
XH-S004 (DPP-1 inhibitor, PO) is being investigated…
Shots:
Merck has entered into a definitive agreement to acquire Verona Pharma incl. its asset Ohtuvayre (ensifentrine), expanding its cardio-pulmonary pipeline & portfolio
As per the deal, Merck will acquire Verona Pharma for $107 per American Depository Share (ADS), each representing 8 ordinary Verona shares, for an aggregate of ~$10B; closing expected in Q4'25
Ohtuvayre…

