Tags : combination

Regeneron Collaborates with BioNTech to Advance the Combination of FixVac

Shots: The two companies collaborated to jointly conduct P-II study combining BNT111 FixVac and Libtayo in patients with anti-PD1-refractory/relapsed, unresectable Stage III or IV cutaneous melanoma with the expected initiation of the study in Q4’20 The companies will equally share the development costs for the clinical trial and will contribute their products for the trial. […]Read More

AstraZeneca Plans to Advance the Combination of Neutralizing Antibody for

Shots: AstraZeneca has licensed Vanderbilt University’s coronavirus-neutralizing Abs & plans to advance a pair of these mAbs into clinical development as a combination therapy for COVID-19. The agreement follows AstraZeneca and Vanderbilt collaboration in Apr’20 AstraZeneca has evaluated the ability of 1,500+ mAbs to bind to the SARS-CoV-2 virus and inhibit its capacity to infect […]Read More

BMS Signs a Clinical Trial Collaboration with NeoImmune to Evaluate

Shots: NeoImmuneTech to sponsor the trial and BMS will supply Opdivo (nivolumab) for the use in the trial. Additionally, under Master Clinical Trial Collaboration Agreement, the first study will be focusing on gastric/GEJ/EAC cancers and the companies can evaluate additional combination trials in the future The goal of the collaboration is to evaluate preliminary anti-tumor […]Read More

GSK’s Advil Dual Action in Combination with Acetaminophen Receives the

Shots: The approval is based on seven clinical studies including three of which were pivotal efficacy and safety studies in pain relief which involves assessing of ibuprofen (250 mg) + acetaminophen (500 mg) vs ibuprofen and acetaminophen monothx in patients with acute pain symptoms The study demonstrated that the FD combination achieved superior efficacy then […]Read More

BioInvent Collaborates with MSD to Evaluate BI-1206 in Combination with

Shots: The companies collaborate to evaluate the combination of BioInvent’s BI-1206 and MSD’s Keytruda in a P-l/lla clinical study for patients with solid tumors, prior treated with anti-PD-1 or anti-PD-L1 Ab The collaboration allows BioInvent to expand the clinical development of BI-1206 against solid tumors. The preclinical data demonstrated that BI-1206 addresses the mechanism of […]Read More

Kite and Kiniksa Collaborate to Evaluate the Combination of Yescarta

Shots: Kite and Kiniksa enter into a clinical collaboration to conduct a P-II study assessing Yescarta + mavrilimumab in patients with r/r LBCL. Kite will sponsor and conduct the study The P-II study will determine the effect of GM-CSFRα inhibition with mavrilimumab on the clinical safety of Yescarta. The collaboration supports Kiniksa’s objective to develop […]Read More

TB Alliance’s Pretomanid Combination Therapy Receives the US FDA’s Approval

Shots: The approval is based on the Nix-TB trial assessing bedaquiline, pretomanid and linezolid collectively called BPaL regimen in 109 patients with XDR-TB treatment-intolerant or non-responsive MDR-TB across three sites in South Africa The study demonstrated successful outcomes in @6mos. 95/107 patients and for two of the patients the study was extended to nine months. […]Read More