BRENZYS (etanercept injection) now indicated for the Treatment of Plaque Psoriasis, Psoriatic Arthritis and Juvenile Idiopathic Arthritis
- BRENZYS??is a biosimilar biologic drug authorized based on its similarity to ENBREL?, which is already approved for use in?Canada.1
- Approximately one million people in?Canada?live with psoriasis,2?and between 10 and 30% of people with psoriasis will develop psoriatic arthritis.3
- Adult patients with chronic moderate to severe plaque psoriasis (PsO) who are candidates for systemic therapy or phototherapy
- Pediatric patients ages 4 to 17 years with chronic severe PsO who are candidates for systemic therapy or phototherapy
- Reducing signs and symptoms, inhibiting the progression of structural damage of active arthritis and improving physical function in adult patients with psoriatic arthritis (PsA)
- Reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in patients aged 4 to 17 years who have had an inadequate response to one or more disease-modifying antirheumatic drugs (DMARDs).?4
References |
1?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
2?Psoriasis. Canadian Dermatology Foundation. 2020. |
3?Psoriatic Arthritis. Arthritis Society. 2020.?https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/psoriatic-arthritis |
4?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
5?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
6?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
7?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
8?Psoriasis. Canadian Dermatology Foundation. 2020. |
9?Psoriatic Arthritis. Arthritis Society. 2020.?https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/psoriatic-arthritis |
10?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
11?Symptoms. Canadian Association of Psoriasis Patients. 2014. canadianpsoriasis.ca/index.php/en/psoriasis/81-english/psoriasis/94-symptoms#:~:text=About%2080%25%20to%2090%25%20of,with%20silvery%20scales%20on%20top |
12?BRENZYS??Product Monograph. Merck & Co. Inc. August 19, 2020. |
14?6 facts about Juvenile Idiopathic Arthritis. Montreal Children's Hospital. 2020.?https://www.thechildren.com/health-info/conditions-and-illnesses/6-facts-about-juvenile-idiopathic-arthritis |
15?BRENZYS??Product Monograph. Merck & Co. Inc. August 19, 2020. |
16?BRENZYS??Product Monograph. Merck & Co. Inc. August 19, 2020. |
17?Biosimilar Biologic Drugs in Canada: Fact Sheet. Government of Canada. August 27, 2019. |
18?Biosimilar Biologic Drugs in Canada: Fact Sheet. Government of Canada. August 27, 2019. |
19?BRENZYS??Product Monograph. Merck & Co. Inc. August 19, 2020. |
20?BRENZYS??Product Monograph. Merck & Co. Inc. August 19, 2020. |
21?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |
22?BRENZYS? Product Monograph. Merck & Co. Inc. August 19, 2020. |