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Deep Apple Therapeutics Enters a Research Collaboration and Licensing Deal with Novo Nordisk to Advance Oral Small Molecules

Shots:

  • Deep Apple & Novo have partnered to discover, develop, & commercialize oral small molecules targeting novel non-incretin GPCRs for cardiometabolic diseases, incl. obesity, using Deep Apple’s drug discovery tech
  • Novo will gain exclusive global rights to develop, manufacture, & commercialize assets discovered & optimized by Deep Apple for ~$812M in upfront, research costs, & milestones, plus potential royalties; both will co-develop the research plan, with Novo taking over before IND-enabling studies
  • Deep Apple’s tech uses ML-powered virtual screening with cryo-EM-based structural biology to accelerate lead discovery by capturing dynamic GPCR conformations & identifying novel binding pockets for docking with its virtual libraries

Ref: Prnewswire | Image: Prnewswire | Press Release

Related News:- Novo Nordisk Enters a ~$2.2B Deal with Septerna to Develop Oral Small Molecules for Cardiometabolic Diseases

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