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Horizon Reports the Completion of Patients Enrollment of Tepezza (teprotumumab-trbw) in the P-III (OPTIC-J) Trial for the Treatment of Active Thyroid Eye Disease

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Horizon Reports the Completion of Patients Enrollment of Tepezza (teprotumumab-trbw) in the P-III (OPTIC-J) Trial for the Treatment of Active Thyroid Eye Disease

Horizon Reports the Completion of Patients Enrollment of Tepezza (teprotumumab-trbw) in the P-III (OPTIC-J) Trial for the Treatment of Active Thyroid Eye Disease

Shots:

  • The company has completed the patient enrollment of the P-III (OPTIC-J) trial evaluating the efficacy, tolerability & safety of Tepezza (q3w) vs PBO in a ratio (1:1) in patients with active TED in Japan. Patients will be eligible to enter an OLE period to receive an additional 8 infusions of Tepezza upon the completion of the treatment period & are proptosis non-responders @24wk.
  • The primary efficacy EPs was proptosis response rate @24wk. as measured by the percentage of patients with a 2mm reduction in proptosis from baseline without deterioration in the fellow eye
  • Tepezza was approved in the US in Jan 2020 & was the first medicine used to treat TED. The therapy has not been approved for commercial use in Japan

Ref: Horizon  | Image: Horizon

Click here to­ read the full press release 

Neha

Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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