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Merck Reports Results of Keytruda (pembrolizumab) in P-III (KEYNOTE-091) Trial as Adjuvant Treatment for Stage IB-IIIA NSCLC

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Merck Reports Results of Keytruda (pembrolizumab) in P-III (KEYNOTE-091) Trial as Adjuvant Treatment for Stage IB-IIIA NSCLC

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  • The P-III (KEYNOTE-091) trial evaluates Keytruda (200mg, IV, q3w) vs PBO in a ratio (1:1) in 1,177 patients with stage IB-IIIA NSCLC following surgical resection with/out adjuvant CT
  • The trial met its 1EPs of DFS for patients with stage IB-IIIA NSCLC regardless of PD-L1 expression. In an interim analysis, the therapy showed an improvement in DFS in the all-comer population & whose tumors express PD-L1. The safety profile was consistent with previously reported studies
  • The company has an extensive clinical development program in lung cancer. Keytruda is being evaluated in multiple registration-enabling studies in combination with other treatments & as monothx. for lung cancer

Ref: Businesswire | Image: Merck

Click here to­ read the full press release 

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