Merck's Keytruda (pembrolizumab) Receives the US FDA's Approval as an Adjuvant Therapy for Renal Cell Carcinoma
Shots:
- The approval is based on the P-III KEYNOTE-564 trial evaluating Keytruda (200mg, IV, q3w for 1yrs.) vs PBO in a ratio (1:1) in 994 patients with intermediate-high or high risk of recurrence of RCC or M1 NED, following nephrectomy and resection of metastatic lesions
- The results showed an improvement in DFS, 32% reduction in the risk of disease recurrence or death & the median duration of exposure was 11.1mos.
- Merck has a broad clinical development program exploring Keytruda, as monothx. or in combination, as well as other investigational products across multiple settings and stages of RCC, including adjuvant and advanced or metastatic disease
Ref: Merck | Image: Merck
Click here to read the full press release
This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com