Shots:

• The P-III M15-736 Study evaluates the efficacy, safety & tolerability of ABBV-951 to levodopa/carbidopa in 130 adult patients with advanced PD across 80 sites globally
• The study met its 1EPs of increase from baseline in "On" time (hours) without troublesome dyskinesia after 12wks. based on PD Diary. The therapy also showed an improvement from baseline in hrs. of average daily normalized "Off" time that followed a similar pattern in reductions after 1st wks. through 12wks. & was superior to levodopa/carbidopa in reducing motor fluctuations
• Additionally, AEs were consistent with the well-established safety profile of levodopa/carbidopa, treatment discontinuation due to AEs (21.6% & 1.5%)

 Ref: AbbVie | Image: abbvie