Vifor and Angion's ANG-3777 Fail to Meet its Primary and Secondary Endpoint for Patients with High-Risk Kidney Transplant
Shots:
- The P-III trial evaluates ANG-3777 (qd for 3days) vs PBO in a ratio (1:1) in 253 patients with kidney transplants who were at risk for developing DGF
- The trial failed to show a significant difference from PBO on the 1EPs of eGFR @12mos. The therapy demonstrated an inconsistent benefit on 2EPs. while overall safety profile was consistent with the overall experience in its clinical development program & consistent with the published literature in a patient population
- The results are not expected to support an indication in the studied DGF population. Additionally- the P-II exploratory trial of ANG-3777 for acute kidney injury associated with CSA-AKI is ongoing & results are expected in Q4’21
| Ref: Globe Newswire | Image: Businesswire
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