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Apellis Presents 18-Month Results of Pegcetacoplan in P-III (DERBY) and (OAKS) Studies for the Treatment of Geographic Atrophy at ARVO 2022

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Apellis Presents 18-Month Results of Pegcetacoplan in P-III (DERBY) and (OAKS) Studies for the Treatment of Geographic Atrophy at ARVO 2022

Apellis Presents 18-Month Results of Pegcetacoplan in P-III (DERBY) and (OAKS) Studies for the Treatment of Geographic Atrophy at ARVO 2022

Shots:

  • The P-III (DERBY) & (OAKS) studies evaluate pegcetacoplan (IVI) in 621 & 637 patients with GA related to AMD. The company plans to submit an NDA to the US FDA in Q2’22
  • The results showed a reduction in extrafoveal & foveal GA lesion growth in (OAKS) study by 33% & 18% in qm; 17% & 19% in every-other-mos. In (DERBY) study, 17% & 9% in qm; 23% & 4% in every-other-mos. along with favorable safety profile which was consistent with safety rates @12mos. & longer-term exposure
  • The combined rate of new-onset exudations in qm, every other mos., & sham (9.5%, 6.2%, & 2.9%). The therapy showed a robust effect in patients with extrafoveal lesions & improved effect with foveal lesions

Ref: Globenewswire | Image: Apellis

Click here to­ read the full press release 

Neha

Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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