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Merck Signs a Supply Agreement with Werewolf for WTX-124 INDUKINE Program to Treat Solid Tumors

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Merck Signs a Supply Agreement with Werewolf for WTX-124 INDUKINE Program to Treat Solid Tumors

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  • The companies collaborated to evaluate the safety and preliminary efficacy of Werewolf's WTX-124 as monothx. or in combination with Merck’s Keytruda (anti-PD-1 therapy) in a P-I trial for patients with solid tumors
  • The company plans to submit an IND application for WTX-124 to the US FDA in H2’22
  • WTX-124 is a systemically delivered- conditionally activated IL-2 INDUKINE molecule engineered to minimize the severe toxicities that have been identified with recombinant IL-2 therapy & maximize clinical benefit when used in combination with checkpoint inhibitors in multiple tumor types

  Ref: Globe Newswire | Image: Merck 

Click here to­ read the full press release 

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