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Innovent and AnHeart’s Receive NMPA’s Breakthrough Therapy Designation for Taletrectinib to Treat ROS1-Positive Non-Small Cell Lung Cancer

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Innovent and AnHeart’s Receive NMPA’s Breakthrough Therapy Designation for Taletrectinib to Treat ROS1-Positive Non-Small Cell Lung Cancer

Innovent and AnHeart’s Receive NMPA’s Breakthrough Therapy Designation for Taletrectinib to Treat ROS1-Positive Non-Small Cell Lung Cancer

Shots:

  • The NMPA has granted BTD to taletrectinib for TKI-naïve & pretreated patients with ROS1+ NSCLC
  • The designation was based on the P-II (TRUST) trial of taletrectinib in patients with ROS1 fusion+ NSCLC. At the data cut-off date June 16, 2021, the results showed 90.5% (19/21) ORR & DCR {90.5% (19/21)} in treatment-naïve patient while ORR {43.8% (7/16)}; DCR {75.0% (12/16)} in the pre-treated patient
  • The therapy showed promising efficacy in patients with resistant G2032R mutation, intracranial antitumor activity in brain metastatic patients with neurological AEs & was well-tolerated. Taletrectinib is a ROS1 inhibitor & is designed to target ROS1 fusion mutations for both patients

Ref: PR Newswire | Image: Fierce Pharma

Click here to­ read the full press release 

Neha

Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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