Logo

Samsung Bioepis Presents Five-year Follow-up Results of Ontruzant (biosimilar- trastuzumab) in Early or Locally Advanced HER2 Positive Breast Cancer at ESMO 2021

Share this
Samsung Bioepis Presents Five-year Follow-up Results of Ontruzant (biosimilar- trastuzumab) in Early or Locally Advanced HER2 Positive Breast Cancer at ESMO 2021

Samsung Bioepis Presents Five-year Follow-up Results of Ontruzant (biosimilar- trastuzumab) in Early or Locally Advanced HER2 Positive Breast Cancer at ESMO 2021

Shots:

  • The P-III study evaluates the cardiac safety profiles & efficacy of Ontruzant vs reference trastuzumab in 367 patients with HER2 positive early or LA BC for 4yrs. after randomization
  • Patients were randomized to receive 8 cycles of either Ontruzant or TRZ with concurrent neoadjuvant CT. After surgery- patients received 10 cycles of biosimilar trastuzumab or TRZ completing 1yrs. of treatment
  • In follow up study- the reduction in asymptomatic LVEF at both groups- 3 patients recovering with LVEF ≥ 50%- no cases of heart failure or cardiac death observed- EFS rates (82.8% vs 79.7%)- OS rates (93.1% vs 86.7%)- number of events i.e. recurrence- progression- or death (17.2% vs 21%)

  | Ref: Globe Newswire | Image: Samsung Bioepis

Click here to­ read the full press release 

Tuba

Tuba Khan is Senior Editor at PharmaShots. She is curious, creative, and passionate about recent updates and innovation in the Life sciences industry. She covers Biopharma, MedTech, and Digital health segments. Tuba also has an experience of digital and social media marketing and runs the campaigns independently. She can be contacted on connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Related News/Articles

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions