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Hepion Reports Results of CRV431 in P-IIa AMBITION Trial for the Treatment of NASH

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Hepion Reports Results of CRV431 in P-IIa AMBITION Trial for the Treatment of NASH

Hepion Reports Results of CRV431 in P-IIa AMBITION Trial for the Treatment of NASH

Shots:

  • The P-IIa AMBITION study assessing CRV431 (75/ 225mg- qd- PO given as soft gelatin capsules) vs PBO to presumed F2 and F3 NASH patients for 28days- followed by a 14-day observation period for safety
  • The study met its 1EPs i.e. safety- tolerability & PK with no SAEs at both doses while some patients experienced mild AEs- reductions in liver transaminases indicate dose-related improvements in NASH biomarker- decrease ALT AUCs with increase dose indicating a positive dose-response
  • The company plans to initiate the P-IIb ASCEND-NASH trial in 2021 to evaluate CRV431 in biopsy-proven NASH patients with advanced fibrosis

  Ref: Globe Newswire | Image: Hepion Pharma

Click here to­ read the full press release 

Tuba

Tuba Khan is Senior Editor at PharmaShots. She is curious, creative, and passionate about recent updates and innovation in the Life sciences industry. She covers Biopharma, MedTech, and Digital health segments. Tuba also has an experience of digital and social media marketing and runs the campaigns independently. She can be contacted on connect@pharmashots.com

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