Shots:

• The US FDA approved Kloxxado (Nasal Spray- 8mg) for the emergency treatment of opioid overdose observed in respiratory and/or CNS depression in adult and pediatric patients.
• In a survey- Narcan (Nasal Spray- 4mg) showed 34% attempted reversals used two or more doses. A separate study published in 2019 showed that the percent of overdose-related emergencies in the US requiring multiple doses of naloxone during 2013-2016 increased to 21% which represented a 43% increase over 4 years
• Kloxxado contains double the amount of naloxone per spray as Narcan in a ready-to-use nasal spray and it is expected to be available in H2’ 21

  Ref: PRNewswire | Image: Hikma