Logo

Merck KGaA's Tepmetko (tepotinib) Receives the US FDA's Approval for Patients with Metastatic NSCLC with METex14 Skipping Alterations

Share this

Merck KGaA's Tepmetko (tepotinib) Receives the US FDA's Approval for Patients with Metastatic NSCLC with METex14 Skipping Alterations

Shots:

  • The approval is based on pivotal P- II VISION study that involves assessing of Tepmetko (450mg- qd) as monothx. in 152 patients with a median age of 73 years with advanced/ m-NSCLC with METex14 skipping alterations
  • Results: treatment-naïve patients & previously treated patients- ORR (43% & 43%); mDoR (0.8 and 11.1mos.); DoR @6mos. (67% & 75%); DoR @9mos. (30% & 50%) respectively
  • Tepmetko is an oral MET inhibitor that inhibits the oncogenic MET receptor signaling caused by MET (gene) alterations and approved for both treatment naïve and previously treated METex14 positive NSCLC patients

 ­ Ref: PRNewswire | Image: Merck KGaA

Click here to­ read the full press release 

Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions