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Linnaeus Reports First Patients Dosing with LNS8801 + Keytruda (pembrolizumab) in P-I/II Study for Advanced Cancer

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Linnaeus Reports First Patients Dosing with LNS8801 + Keytruda (pembrolizumab) in P-I/II Study for Advanced Cancer

Shots:

  • The first patient has been dosed in P-l/ll adaptive-design study assessing the safety- tolerability- pharmacokinetics- and antitumor activity of LNS8801+ Keytruda (pembrolizumab) in patients who had previous clinical benefit from immune checkpoint inhibitors and then subsequently progressed
  • The initiation of the study follows the identification of the RP2D in the ongoing study of LNS8801. The company anticipates opening several more phase 2 dose-expansion cohorts exploring LNS8801 activity as a monothx. and in combination with other compounds in 2021
  • LNS8801 (PO) is a bioavailable small molecule that is a highly specific and potent agonist of the GPER and has demonstrated target engagement and clinical benefit in advanced cancer patients. P-l/ll study’s results are anticipated to be presented in a peer-reviewed setting in 2021

     Ref: PRNewswire | Image: PRNewswire
Click here to­ read the full press release 

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