GSK's Blenrep (belantamab mafodotin-blmf) Receives the US FDA's Approval as a Monotherapy Treatment for Multiple Myeloma
Shots:
- The approval is based on a pivotal study- DREAMM-2 assessing Blenrep (2.5 mg/kg- q3w) in 218 patients with relapsed or refractory multiple myeloma who had actively progressing disease that had worsened despite current SoC
- Results: Blenrep demonstrated an ORR (31%)- DoR not reached at the 6-mos. analysis- but 73% of responders had a DoR ≥ 6 mos. Continued approval for this indication depends upon verification and description of clinical benefit in confirmatory trials
- Blenrep (belantamab mafodotin-blmf) is an antibody drug conjugate comprising a humanised anti-B cell maturation antigen (BCMA) monoclonal antibody conjugated to the cytotoxic agent auristatin F. Blenrep is the 1st anti-BCMA therapy approved globally and 5th major medicine approval for GSK in 2020
Ref: Twitter | Image: GSK
Click here to read the full press release
Tags
This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com