Shots:

• The acceptance of sNDA is based on P-III ORIENT-32 study assessing in sintilimab + bevacizumab vs sorafenib in 571 subjects in a ratio (2:1) as 1L treatment for patients with advanced HCC
• The study met the pre-defined efficacy criteria which showed significant improvement in OS and PFS as assessed by IRRC
• This marks the fifth NDA application of Tyvyt that has been accepted for review by NMPA. Meanwhile- the application also seeks the fourth indication for Byvasda

 ­ Ref: Innovent Bio | Image: Innovent