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Kite Reports Results of Yescarta (axicabtagene ciloleucel) in ZUMA-1 trial for Refractory Large B-Cell- Lymphoma- Presented at ASH 2018

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Kite Reports Results of Yescarta (axicabtagene ciloleucel) in ZUMA-1 trial for Refractory Large B-Cell- Lymphoma- Presented at ASH 2018

Shots:
  • The ZUMA-1 trial involves assessing of Yescarta in patients with refractory large B-cell lymphoma for a duration of two years
  • ZUMA-1 trial results (N=101): OR 83%; CR 58%; median follow up @27.1- 24 mos. (39%- 93% remain in response); mDOR 11.1 mos.; with no new safety signals observed
  • Yescarta (axicabtagene ciloleucel) is novel CAR T therapy approved by FDA for 2L+ r/r large B-cell lymphoma. The US PI involves a box warning with the usage of Yescarta leading to Cytokine Release Syndrome (CRS) & Neurologic toxicities
Ref: Kite | Image: Eideard

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