Sanofi Signs an Agreement with Kymera to Advance Novel Protein Degrader Therapies Worth Up to $2.1B
Shots:
- Kymera to receive $150M up front- $2B as development- regulatory and commercial milestones along with royalties on sales of therapies. Additionally- the company has an option to develop and commercialize the two programs in the US while retaining global rights to its IRAK4 program in oncology indications.
- Sanofi will get a global right to develop and commercialize protein degrader therapies targeting IRAK4 in patients with immune-inflammatory diseases and a second undisclosed preclinical program
- Kymera will advance the IRAK4 program through the P-I study- afterward- Sanofi will be further responsible for its development and will lead all clinical development activities for the second program. IRAK4 is a key protein involved in inflammation mediated by the activation of TLRs and IL-1Rs
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