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Kodiak Sciences Reports P-III (DAYBREAK) Trial Data on Zenkuda and Tabirafusp-ted for wAMD

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  • Kodiak has reported the P-III (DAYBREAK) trial data assessing Zenkuda (tarcocimab tedromer) and tabirafusp-ted (KSI-501) in parallel vs aflibercept in pts with wet age-related macular degeneration (wAMD)
  • Zenkuda met its 1EP, showing meaningful vision gains & rapid, sustained retinal drying, with 54% of pts achieving 6mos. durability at Yr. 1. tabirafusp-ted also met its vision 1EP & anatomical key 2EP
  • Post-hoc analyses is planned to identify wAMD subgroups that may benefit from IL-6 inhibition, while P-III (ALTO) of KSI-501 for DME is currently enrolling. Kodiak plans to submit three-indication BLA for Zenkuda in Q4’26

Ref: PRnewswire   |   Image:  Kodiak Sciences   |  Press Release

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