Shots:

• AstraZeneca has licensed Vanderbilt University’s coronavirus-neutralizing Abs & plans to advance a pair of these mAbs into clinical development as a combination therapy for COVID-19. The agreement follows AstraZeneca and Vanderbilt collaboration in Apr’20
• AstraZeneca has evaluated the ability of 1-500+ mAbs to bind to the SARS-CoV-2 virus and inhibit its capacity to infect healthy cells in a laboratory setting. Based on pre-clinical results- the company has signed an exclusive license to six Abs currently in Vanderbilt’s portfolio targeting COVID-19. 2 out of 6 mAbs will progress into clinical evaluation as a combination approach within the next 2mos.
• Additionally- AstraZeneca has signed an interagency agreement with DARPA and BARDA to support the development of mAb against COVID-19 including P-I clinical study and the manufacturing of the investigational product for testing in P-I

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Ref: AstraZeneca | Image: AstraZeneca