AstraZeneca Reports the P-III (EMERALD-3) Trial Data on Imfinzi Combination + TACE in Unresectable Hepatocellular Carcinoma
Shots:
- The P-III (EMERALD-3) trial assessed single priming dose of Imjudo (300mg) + Imfinzi (1500mg) followed by Imfinzi (Q4W) + transarterial chemoembolisation (TACE) ± lenvatinib vs TACE alone in 760 pts unresectable HCC eligible for embolization
- Imjudo + Imfinzi + Lenvatinib & TACE showed improved PFS (1EP) vs TACE alone, with OS (2EP) demonstrating a favorable trend in the interim analysis
- Also, Single Imjudo regular interval Imfinzi regimen + TACE showed trends toward improved PFS & OS vs TACE alone, while OS & other key 2EPs will be evaluated further; data will be presented at a future meeting & shared with global regulatory authorities
Ref: AstraZeneca | Image: AstraZeneca | Press Release
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