Novocure Reports Topline P-II (PANOVA-4) Trial Data on TTFields Therapy for Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)
Shots:
- Novocure reported P-II (PANOVA-4) trial data evaluating Tumor Treating Fields (TTFields) with Tecentriq & gemcitabine/nab-paclitaxel as a 1L treatment for mPDAC, with a median TTFields duration of 25.6wks. & median systemic therapy duration of 6 cycles
- Trial met its 1EP, showing a DCR of 74.4% in TTFields group (N=78) vs 48% with gem/nab-pac alone (N=431) from the historical P-III (MPACT) trial control
- Trial also showed improvements across 2EPs, incl. ORR of 34.6% & mOS of 9.7mos. Additional 2EPs incl. PFS, one-year survival rate, 6mos. PFS, DoR, & rate of TRAEs; additional data to be presented at future conference
Ref: Businesswire | Image: Novocure| Press Release
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