Roche Collaborates with Celleron Therapeutics for Emactuzumab to Treat Patients with Tenosynovial Giant Cell Tumor
Shots:
- Celleron will receive an exclusive global right for the clinical development- manufacturing- and commercialization of emactuzumab (formerly RG7155 and RO5509554). The companies expect the closing of an agreement by the end of 2020
- 86% of TGCT patients treated with emactuzumab responded to the drug- with 68% of people experiencing a PR within 6 weeks of starting the treatment. The license agreement demonstrated Celleron’s dedication to the development of cancer medicine and its transformational potential for patients inflicted with cancer
- Emactuzumab (RG7155) is an IgG1 mAb- designed to target and deplete macrophages in the tumor tissue. The therapy targets TAMs by binding to CSF-1R on the cell surface and blocking its activation by CSF-1
Ref: Celleron Therapeutics | Image: Roche
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